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Quercetin induced ROS production triggers mitochondrial cell death of human embryonic stem cells

Small molecules to selectively induce cell death of undifferentiated human pluripotent stem cells (hPSCs) have been developed with the aim of lowering the risk of teratoma formation during hPSC-based cell therapy. In this context, we have reported that Quercetin (QC) induces cell death selectively i...

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Detalles Bibliográficos
Autores principales: Kim, So-Yeon, Jeong, Ho-Chang, Hong, Soon-Ki, Lee, Mi-Ok, Cho, Seung-Ju, Cha, Hyuk-Jin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630304/
https://www.ncbi.nlm.nih.gov/pubmed/29029404
http://dx.doi.org/10.18632/oncotarget.11070