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RNAi targeting Nogo Receptor enhanced survival and proliferation of murine retinal ganglion cells during N-methyl-D-aspartate-induced optic nerve crush

We investigated the effects of lentivirus-mediated RNAi targeting of Nogo Receptor (NgR) on the proliferation and survival of murine retinal ganglion cells (mRGCs) in vitro and in vivo. Cultured mRGCs and C57BL/6 male mice were divided into 4 experimental groups: blank, model [100 μM N-methyl-D-aspa...

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Detalles Bibliográficos
Autores principales: Zeng, Kun, Zhong, Bo, Shen, Xiao-Li, Fang, Min, Lin, Bao-Tao, Ma, Da-Hui
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630308/
https://www.ncbi.nlm.nih.gov/pubmed/29029408
http://dx.doi.org/10.18632/oncotarget.17351