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RNAi targeting Nogo Receptor enhanced survival and proliferation of murine retinal ganglion cells during N-methyl-D-aspartate-induced optic nerve crush
We investigated the effects of lentivirus-mediated RNAi targeting of Nogo Receptor (NgR) on the proliferation and survival of murine retinal ganglion cells (mRGCs) in vitro and in vivo. Cultured mRGCs and C57BL/6 male mice were divided into 4 experimental groups: blank, model [100 μM N-methyl-D-aspa...
Autores principales: | Zeng, Kun, Zhong, Bo, Shen, Xiao-Li, Fang, Min, Lin, Bao-Tao, Ma, Da-Hui |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630308/ https://www.ncbi.nlm.nih.gov/pubmed/29029408 http://dx.doi.org/10.18632/oncotarget.17351 |
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