Cargando…

A20 functions as mediator in TNFα-induced injury of human umbilical vein endothelial cells through TAK1-dependent MAPK/eNOS pathway

A20, a negative regulator of nuclear factor κB signaling, has been shown to attenuate atherosclerotic events. Transforming growth factor beta-activated kinase 1 (TAK1) plays a critical role in TNFα-induced atherosclerosis via endothelial nitric oxide (NO) synthase (eNOS) uncoupling and NO reduction....

Descripción completa

Detalles Bibliográficos
Autores principales: Li, Lei, Huang, Bingqing, Song, Shiyang, Sohun, Hareshwaree, Rao, Zhiheng, Tao, Luyuan, Jin, Qike, Zeng, Jingjing, Wu, Rongzhou, Ji, Kangting, Lin, Jiafeng, Wu, Lianpin, Chu, Maoping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630326/
https://www.ncbi.nlm.nih.gov/pubmed/29029426
http://dx.doi.org/10.18632/oncotarget.18191