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Methylomics of nitroxidative stress on precancerous cells reveals DNA methylation alteration at the transition from in situ to invasive cervical cancer

Epigenetic dysregulation is important in cervical cancer development, but the underlying mechanism is largely unknown. Increasing evidence indicates that DNA methylation is sensitive to changes in microenvironmental factors, such as nitric oxide (NO) in the chronic inflammatory cervix. However, the...

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Detalles Bibliográficos
Autores principales: Su, Po-Hsuan, Hsu, Yao-Wen, Huang, Rui-Lan, Weng, Yu-Chun, Wang, Hui-Chen, Chen, Yu-Chih, Tsai, Yueh-Ju, Yuan, Chiou-Chung, Lai, Hung-Cheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630330/
https://www.ncbi.nlm.nih.gov/pubmed/29029430
http://dx.doi.org/10.18632/oncotarget.18370