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XIST/miR-139 axis regulates bleomycin (BLM)-induced extracellular matrix (ECM) and pulmonary fibrosis through β-catenin

Pulmonary fibrosis (PF), characterized by the destruction of lung tissue architecture and the abnormal deposition of extracellular matrix (ECM) proteins, currently has no satisfactory treatment. In the present study, we investigated the hypothesis that XIST play a promotive role in bleomycin (BLM)-i...

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Detalles Bibliográficos
Autores principales: Wang, Yichun, Liang, Ying, Luo, Junming, Nie, Jing, Yin, Huiming, Chen, Qiong, Dong, Jing, Zhu, Jixiang, Xia, Jiamei, Shuai, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630336/
https://www.ncbi.nlm.nih.gov/pubmed/29029436
http://dx.doi.org/10.18632/oncotarget.18310