Mobilization studies in mice deficient in sphingosine kinase 2 support a crucial role of the plasma level of sphingosine-1-phosphate in the egress of hematopoietic stem progenitor cells

Sphingosine-1-phosphate (S1P) is a bioactive lipid involved in cell signaling and, if released from cells, also plays a crucial role in regulating the trafficking of lympho-hematopoietic cells, including primitive hematopoietic stem/progenitor cells (HSPCs). It has been demonstrated that S1P chemoat...

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Detalles Bibliográficos
Autores principales: Adamiak, Mateusz, Chelvarajan, Lakshman, Lynch, Kevin R., Santos, Webster L., Abdel-Latif, Ahmed, Ratajczak, Mariusz Z.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630355/
https://www.ncbi.nlm.nih.gov/pubmed/29029455
http://dx.doi.org/10.18632/oncotarget.19514

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630355/
https://www.ncbi.nlm.nih.gov/pubmed/29029455
http://dx.doi.org/10.18632/oncotarget.19514

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