VRK1 promotes cisplatin resistance by up-regulating c-MYC via c-Jun activation and serves as a therapeutic target in esophageal squamous cell carcinoma

Esophageal squamous cell carcinoma (ESCC) is a common malignant disease characterized by poor prognosis. Chemoresistance remains a major cause of ESCC relapse. Vaccinia-related kinase 1 (VRK1) has previously been identified as a cancer-related gene. However, there is little research demonstrating an...

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Detalles Bibliográficos
Autores principales: Liu, Zhen-Chuan, Cao, Kuo, Xiao, Zhao-Hua, Qiao, Liang, Wang, Xue-Qing, Shang, Bin, Jia, Yang, Wang, Zhou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630360/
https://www.ncbi.nlm.nih.gov/pubmed/29029460
http://dx.doi.org/10.18632/oncotarget.20020

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630360/
https://www.ncbi.nlm.nih.gov/pubmed/29029460
http://dx.doi.org/10.18632/oncotarget.20020

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