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Alterations in DNA methylation/demethylation intermediates predict clinical outcome in chronic lymphocytic leukemia

Cytosine derivative dysregulations represent important epigenetic modifications whose impact on the clinical outcome in chronic lymphocytic leukemia (CLL) is incompletely understood. Hence, global levels of 5-methylcytosine (5-mCyt), 5-hydroxymethylcytosine (5-hmCyt), 5-carboxylcytosine (5-CaCyt) an...

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Detalles Bibliográficos
Autores principales: Bagacean, Cristina, Tempescul, Adrian, Le Dantec, Christelle, Bordron, Anne, Mohr, Audrey, Saad, Hussam, Olivier, Valerie, Zdrenghea, Mihnea, Cristea, Victor, Cartron, Pierre-François, Douet-Guilbert, Nathalie, Berthou, Christian, Renaudineau, Yves
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630365/
https://www.ncbi.nlm.nih.gov/pubmed/29029465
http://dx.doi.org/10.18632/oncotarget.20081