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Resveratrol promotes MICA/B expression and natural killer cell lysis of breast cancer cells by suppressing c-Myc/miR-17 pathway

Major histocompatibility complex class I chain-related proteins A and B (MICA and MICB) are important ligands for recognition of tumor cells by immune effector cells. Here, we report that resveratrol upregulated the protein and mRNA expression of MICA and MICB in breast cancer cells, which in turn p...

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Detalles Bibliográficos
Autores principales: Pan, Jie, Shen, Jiaying, Si, Wengong, Du, Chengyong, Chen, Danni, Xu, Liang, Yao, Minya, Fu, Peifen, Fan, Weimin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630368/
https://www.ncbi.nlm.nih.gov/pubmed/29029468
http://dx.doi.org/10.18632/oncotarget.19445