The genetically engineered drug rhCNB induces apoptosis via a mitochondrial route in tumor cells

The calcineurin B subunit (CNB) has antitumor activity. We showed previously that recombinant human CNB (rhCNB) also had strong anti-tumor activity in vivo, and was thus a promising candidate anti-tumor drug. It appeared to kill tumor cells via immunomodulation. Here, we show that rhCNB inhibits the...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Yang, Huan, Yang, Jinju, Li, Li, Xiang, Benqiong, Wei, Qun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630379/
https://www.ncbi.nlm.nih.gov/pubmed/29029479
http://dx.doi.org/10.18632/oncotarget.19507

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630379/
https://www.ncbi.nlm.nih.gov/pubmed/29029479
http://dx.doi.org/10.18632/oncotarget.19507

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