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Cell cycle specific radiosensitisation by the disulfiram and copper complex

The disulfiram and copper complex (DSF:Cu) has emerged as a potent radiosensitising anti-cancer agent. The ability of copper to stabilise DSF in a planar conformation and to inhibit DNA replication enzymes stimulated our investigation of the effect of DSF:Cu on cell cycle regulation. Flow cytometry...

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Detalles Bibliográficos
Autores principales: Tesson, Mathias, Anselmi, Giorgio, Bell, Caitlin, Mairs, Robert
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630381/
https://www.ncbi.nlm.nih.gov/pubmed/29029481
http://dx.doi.org/10.18632/oncotarget.19539