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Cell cycle specific radiosensitisation by the disulfiram and copper complex
The disulfiram and copper complex (DSF:Cu) has emerged as a potent radiosensitising anti-cancer agent. The ability of copper to stabilise DSF in a planar conformation and to inhibit DNA replication enzymes stimulated our investigation of the effect of DSF:Cu on cell cycle regulation. Flow cytometry...
Autores principales: | Tesson, Mathias, Anselmi, Giorgio, Bell, Caitlin, Mairs, Robert |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630381/ https://www.ncbi.nlm.nih.gov/pubmed/29029481 http://dx.doi.org/10.18632/oncotarget.19539 |
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