EGF stimulates glioblastoma metastasis by induction of matrix metalloproteinase-9 in an EGFR-dependent mechanism

Epidermal growth factor (EGF) and EGF receptor (EGFR) play prominent roles in the metastasis of glioblastoma (GBM). However, the molecular mechanisms for the function of EGF and EGFR in GBM metastasis have not been elucidated. Herein, we demonstrate that coactivation of EGF and EGFR drives tumor met...

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Detalles Bibliográficos
Autores principales: Chen, Xing-Chen, Wei, Xiang-Tai, Guan, Jun-Hong, Shu, Hong, Chen, Duo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630386/
https://www.ncbi.nlm.nih.gov/pubmed/29029486
http://dx.doi.org/10.18632/oncotarget.19622

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630386/
https://www.ncbi.nlm.nih.gov/pubmed/29029486
http://dx.doi.org/10.18632/oncotarget.19622

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