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The deubiquitinating enzyme USP5 promotes pancreatic cancer via modulating cell cycle regulators

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid tumors. With an overall five-year survival rate remaining below 6%, there is an explicit need to search for new molecular targets for therapeutic interventions. We undertook a barcode labelled short-hairpin (shRNA) library scree...

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Detalles Bibliográficos
Autores principales: Kaistha, Brajesh P., Krattenmacher, Anja, Fredebohm, Johannes, Schmidt, Harald, Behrens, Diana, Widder, Miriam, Hackert, Thilo, Strobel, Oliver, Hoheisel, Jörg D., Gress, Thomas M., Buchholz, Malte
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630405/
https://www.ncbi.nlm.nih.gov/pubmed/29029505
http://dx.doi.org/10.18632/oncotarget.19882