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The deubiquitinating enzyme USP5 promotes pancreatic cancer via modulating cell cycle regulators
Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal solid tumors. With an overall five-year survival rate remaining below 6%, there is an explicit need to search for new molecular targets for therapeutic interventions. We undertook a barcode labelled short-hairpin (shRNA) library scree...
Autores principales: | Kaistha, Brajesh P., Krattenmacher, Anja, Fredebohm, Johannes, Schmidt, Harald, Behrens, Diana, Widder, Miriam, Hackert, Thilo, Strobel, Oliver, Hoheisel, Jörg D., Gress, Thomas M., Buchholz, Malte |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630405/ https://www.ncbi.nlm.nih.gov/pubmed/29029505 http://dx.doi.org/10.18632/oncotarget.19882 |
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