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Melflufen - a peptidase-potentiated alkylating agent in clinical trials

Aminopeptidases like aminopeptidase N (APN, also known as CD13) play an important role not only in normal cellular functioning but also in the development of cancer, including processes like tumor cell invasion, differentiation, proliferation, apoptosis, motility, and angiogenesis. An increased expr...

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Detalles Bibliográficos
Autores principales: Wickström, Malin, Nygren, Peter, Larsson, Rolf, Harmenberg, Johan, Lindberg, Jakob, Sjöberg, Per, Jerling, Markus, Lehmann, Fredrik, Richardson, Paul, Anderson, Kenneth, Chauhan, Dharminder, Gullbo, Joachim
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630444/
https://www.ncbi.nlm.nih.gov/pubmed/29029544
http://dx.doi.org/10.18632/oncotarget.18420