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Impact of sequencing depth and read length on single cell RNA sequencing data of T cells

Single cell RNA sequencing (scRNA-seq) provides great potential in measuring the gene expression profiles of heterogeneous cell populations. In immunology, scRNA-seq allowed the characterisation of transcript sequence diversity of functionally relevant T cell subsets, and the identification of the f...

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Detalles Bibliográficos
Autores principales: Rizzetto, Simone, Eltahla, Auda A., Lin, Peijie, Bull, Rowena, Lloyd, Andrew R., Ho, Joshua W. K., Venturi, Vanessa, Luciani, Fabio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630586/
https://www.ncbi.nlm.nih.gov/pubmed/28986563
http://dx.doi.org/10.1038/s41598-017-12989-x