Replication defective viral genomes exploit a cellular pro-survival mechanism to establish paramyxovirus persistence

Replication defective viral genomes (DVGs) generated during virus replication are the primary triggers of antiviral immunity in many RNA virus infections. However, DVGs can also facilitate viral persistence. Why and how these two opposing functions of DVGs are achieved remain unknown. Here we report...

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Detalles Bibliográficos
Autores principales: Xu, Jie, Sun, Yan, Li, Yize, Ruthel, Gordon, Weiss, Susan R., Raj, Arjun, Beiting, Daniel, López, Carolina B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630589/
https://www.ncbi.nlm.nih.gov/pubmed/28986577
http://dx.doi.org/10.1038/s41467-017-00909-6

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630589/
https://www.ncbi.nlm.nih.gov/pubmed/28986577
http://dx.doi.org/10.1038/s41467-017-00909-6

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