Cargando…
Replication defective viral genomes exploit a cellular pro-survival mechanism to establish paramyxovirus persistence
Replication defective viral genomes (DVGs) generated during virus replication are the primary triggers of antiviral immunity in many RNA virus infections. However, DVGs can also facilitate viral persistence. Why and how these two opposing functions of DVGs are achieved remain unknown. Here we report...
Autores principales: | Xu, Jie, Sun, Yan, Li, Yize, Ruthel, Gordon, Weiss, Susan R., Raj, Arjun, Beiting, Daniel, López, Carolina B. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2017
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630589/ https://www.ncbi.nlm.nih.gov/pubmed/28986577 http://dx.doi.org/10.1038/s41467-017-00909-6 |
Ejemplares similares
-
Exploiting Connections for Viral Replication
por: Wong, Louise H., et al.
Publicado: (2021) -
Analysis of Paramyxovirus Transcription and Replication by High-Throughput Sequencing
por: Wignall-Fleming, Elizabeth B., et al.
Publicado: (2019) -
Viral evolution identifies a regulatory interface between paramyxovirus polymerase complex and nucleocapsid that controls replication dynamics
por: Sourimant, Julien, et al.
Publicado: (2020) -
C Proteins: Controllers of Orderly Paramyxovirus Replication and of the Innate Immune Response
por: Siering, Oliver, et al.
Publicado: (2022) -
HIV Exploits Antiviral Host Innate GCN2-ATF4 Signaling for Establishing Viral Replication Early in Infection
por: Jiang, Guochun, et al.
Publicado: (2017)