Regulation of Sirtuin 3-Mediated Deacetylation of Cyclophilin D Attenuated Cognitive Dysfunction Induced by Sepsis-Associated Encephalopathy in Mice

The present study aimed to investigate cognitive dysfunction in the hippocampus induced by sepsis-associated encephalopathy (SAE) via acetylation of cyclophilin D (CypD) and opening of mitochondrial permeability transition pore. It also explored whether activating sirtuin 3 (SIRT3) can mediate deace...

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Detalles Bibliográficos
Autores principales: Sun, Fan, Si, Yanna, Bao, Hongguang, Xu, Yajie, Pan, XiaoXiao, Zeng, Lingqing, Jing, Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630658/
https://www.ncbi.nlm.nih.gov/pubmed/28236057
http://dx.doi.org/10.1007/s10571-017-0476-2

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630658/
https://www.ncbi.nlm.nih.gov/pubmed/28236057
http://dx.doi.org/10.1007/s10571-017-0476-2

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