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Identification and validation of uterine stimulant methylergometrine as a potential inhibitor of caspase-1 activation

Inflammasomes are intracellular multiprotein complexes of the innate immune system. Upon an inflammatory insult, such as infection or intracellular damage, a nucleotide-binding oligomerization domain-like receptor (NLR) sensor protein and the adaptor protein ASC (apoptosis-associated speck-like prot...

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Detalles Bibliográficos
Autores principales: García-Laínez, Guillermo, Sancho, Mónica, García-Bayarri, Vanessa, Orzáez, Mar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630661/
https://www.ncbi.nlm.nih.gov/pubmed/28755170
http://dx.doi.org/10.1007/s10495-017-1405-z