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CpG-ODN Facilitates Effective Intratracheal Immunization and Recall of Memory against Neoantigen-Expressing Alveolar Cells

Intrapulmonary immune reactions are impaired by the tolerogenic environment of the lung. This is manifested by the absence of effective endogenous T cell responses upon neoantigen expression. This tolerance is considered to contribute to lung cancer and inefficient immune therapeutic interventions....

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Detalles Bibliográficos
Autores principales: Riehn, Mathias, Cebula, Marcin, Hauser, Hansjörg, Wirth, Dagmar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630691/
https://www.ncbi.nlm.nih.gov/pubmed/29038654
http://dx.doi.org/10.3389/fimmu.2017.01201