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CpG-ODN Facilitates Effective Intratracheal Immunization and Recall of Memory against Neoantigen-Expressing Alveolar Cells
Intrapulmonary immune reactions are impaired by the tolerogenic environment of the lung. This is manifested by the absence of effective endogenous T cell responses upon neoantigen expression. This tolerance is considered to contribute to lung cancer and inefficient immune therapeutic interventions....
Autores principales: | Riehn, Mathias, Cebula, Marcin, Hauser, Hansjörg, Wirth, Dagmar |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630691/ https://www.ncbi.nlm.nih.gov/pubmed/29038654 http://dx.doi.org/10.3389/fimmu.2017.01201 |
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