Platelet-Derived Chemokine CXCL7 Dimer Preferentially Exists in the Glycosaminoglycan-Bound Form: Implications for Neutrophil–Platelet Crosstalk

Platelet-derived chemokine CXCL7 (also known as NAP-2) plays a crucial role in orchestrating neutrophil recruitment in response to vascular injury. CXCL7 exerts its function by activating the CXC chemokine receptor 2 (CXCR2) receptor and binding sulfated glycosaminoglycans (GAGs) that regulate recep...

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Detalles Bibliográficos
Autores principales: Brown, Aaron J., Sepuru, Krishna Mohan, Sawant, Kirti V., Rajarathnam, Krishna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Immunology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630695/
https://www.ncbi.nlm.nih.gov/pubmed/29038657
http://dx.doi.org/10.3389/fimmu.2017.01248

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630695/
https://www.ncbi.nlm.nih.gov/pubmed/29038657
http://dx.doi.org/10.3389/fimmu.2017.01248

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