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In Silico Prediction Analysis of Idiotope-Driven T–B Cell Collaboration in Multiple Sclerosis

Memory B cells acting as antigen-presenting cells are believed to be important in multiple sclerosis (MS), but the antigen they present remains unknown. We hypothesized that B cells may activate CD4(+) T cells in the central nervous system of MS patients by presenting idiotopes from their own immuno...

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Detalles Bibliográficos
Autores principales: Høglund, Rune A., Lossius, Andreas, Johansen, Jorunn N., Homan, Jane, Benth, Jūratė Šaltytė, Robins, Harlan, Bogen, Bjarne, Bremel, Robert D., Holmøy, Trygve
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630699/
https://www.ncbi.nlm.nih.gov/pubmed/29038659
http://dx.doi.org/10.3389/fimmu.2017.01255