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Unveiling a Drift Resistant Cryptotope within Marburgvirus Nucleoprotein Recognized by Llama Single-Domain Antibodies

Marburg virus (MARV) is a highly lethal hemorrhagic fever virus that is increasingly re-emerging in Africa, has been imported to both Europe and the US, and is also a Tier 1 bioterror threat. As a negative sense RNA virus, MARV has error prone replication which can yield progeny capable of evading c...

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Detalles Bibliográficos
Autores principales: Garza, John Anthony, Taylor, Alexander Bryan, Sherwood, Laura Jo, Hart, Peter John, Hayhurst, Andrew
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630700/
https://www.ncbi.nlm.nih.gov/pubmed/29038656
http://dx.doi.org/10.3389/fimmu.2017.01234