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Good Correlation of Cefiderocol Between In Vivo Efficacy Murine Thigh/Lung Infection Models and MIC Determined in Iron-Depleted Conditions

BACKGROUND: Cefiderocol (S-649266) is a novel siderophore cephalosporin active against a wide variety of carbapenem-resistant Gram-negative bacteria such as Enterobacteriaceae, Pseudomonas aeruginosa, Acinetobacter baumannii and Stenotrophomonas maltophilia. This potent activity is mainly due to its...

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Detalles Bibliográficos
Autores principales: Yamano, Yoshinori, Nakamura, Rio, Sato, Takafumi, Tsuji, Masakatsu, Echols, Roger
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630721/
http://dx.doi.org/10.1093/ofid/ofx163.1220