Immunogenicity and Safety of an Adjuvanted Herpes Zoster Subunit Vaccine in Older Adults Previously Vaccinated with a Live-Attenuated Herpes Zoster Vaccine: A Phase III, Group-Matched, Clinical Trial

BACKGROUND: Herpes zoster (HZ), caused by reactivation of varicella-zoster virus (VZV), typically manifests as a dermatomal rash and can lead to postherpetic neuralgia (PHN). HZ and PHN risk increase with age. Efficacy against HZ induced by a live-attenuated zoster vaccine (ZVL; Merck) declines foll...

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Detalles Bibliográficos
Autores principales: Grupping, Katrijn, Campora, Laura, Douha, Martine, Heineman, Thomas C, Klein, Nicola P, Lal, Himal, Peterson, James, Oostvogels, Lidia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630731/
http://dx.doi.org/10.1093/ofid/ofx163.1038

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630731/
http://dx.doi.org/10.1093/ofid/ofx163.1038

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