Bivalent Norovirus VLP Vaccine Candidate in Older Adults: Impact of MPL and a Second Dose in a Randomized, Controlled, Double-Blind Clinical Trial

BACKGROUND: Acute norovirus (NoV) gastroenteritis may cause significant morbidity in healthy adults and can prove fatal in older subjects. We investigated the safety and immunogenicity in older adults of one or two doses of an intramuscular bivalent virus-like particle (VLP) vaccine candidate (genot...

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Detalles Bibliográficos
Autores principales: Sherwood, Jim, Cramer, Jakob, Cam, Nancy Bouveret Le, Lin, Stella, Baehner, Frank, Mendelman, Paul, Borkowski, Astrid
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630829/
http://dx.doi.org/10.1093/ofid/ofx163.1047

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630829/
http://dx.doi.org/10.1093/ofid/ofx163.1047

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