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CRISPR Diversity and Microevolution in Clostridium difficile

Virulent strains of Clostridium difficile have become a global health problem associated with morbidity and mortality. Traditional typing methods do not provide ideal resolution to track outbreak strains, ascertain genetic diversity between isolates, or monitor the phylogeny of this species on a glo...

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Detalles Bibliográficos
Autores principales: Andersen, Joakim M., Shoup, Madelyn, Robinson, Cathy, Britton, Robert, Olsen, Katharina E.P., Barrangou, Rodolphe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630864/
https://www.ncbi.nlm.nih.gov/pubmed/27576538
http://dx.doi.org/10.1093/gbe/evw203