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The Molecular Chaperone DnaK Is a Source of Mutational Robustness

Molecular chaperones, also known as heat-shock proteins, refold misfolded proteins and help other proteins reach their native conformation. Thanks to these abilities, some chaperones, such as the Hsp90 protein or the chaperonin GroEL, can buffer the deleterious phenotypic effects of mutations that a...

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Detalles Bibliográficos
Autores principales: Aguilar-Rodríguez, José, Sabater-Muñoz, Beatriz, Montagud-Martínez, Roser, Berlanga, Víctor, Alvarez-Ponce, David, Wagner, Andreas, Fares, Mario A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630943/
https://www.ncbi.nlm.nih.gov/pubmed/27497316
http://dx.doi.org/10.1093/gbe/evw176