Essentiality Is a Strong Determinant of Protein Rates of Evolution during Mutation Accumulation Experiments in Escherichia coli

The Neutral Theory of Molecular Evolution is considered the most powerful theory to understand the evolutionary behavior of proteins. One of the main predictions of this theory is that essential proteins should evolve slower than dispensable ones owing to increased selective constraints. Comparison...

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Detalles Bibliográficos
Autores principales: Alvarez-Ponce, David, Sabater-Muñoz, Beatriz, Toft, Christina, Ruiz-González, Mario X., Fares, Mario A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630975/
https://www.ncbi.nlm.nih.gov/pubmed/27566759
http://dx.doi.org/10.1093/gbe/evw205

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5630975/
https://www.ncbi.nlm.nih.gov/pubmed/27566759
http://dx.doi.org/10.1093/gbe/evw205

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