Direct Detection and Quantification of Bacterial Cell-free DNA in Patients with Bloodstream Infection (BSI) Using the Karius Plasma Next Generation Sequencing (NGS) Test

BACKGROUND: Blood cultures can have low sensitivity if a patient is pretreated with antibiotics. A molecular diagnostic for bloodstream infection (BSI) that can also quantitate pathogen DNA could be a useful tool in detecting and monitoring culture-negative infections. METHODS: We prospectively enro...

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Detalles Bibliográficos
Autores principales: Wanda, Lisa, Ruffin, Felicia, Hill-Rorie, Jonathan, Hollemon, Desiree, Seng, Hon, Hong, David, Blauwkamp, Tim, Kertesz, Mickey, Fowler, Vance
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631118/
http://dx.doi.org/10.1093/ofid/ofx163.1613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631118/
http://dx.doi.org/10.1093/ofid/ofx163.1613

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