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Experience with High Dose Once-daily Vancomycin for Patients with Skin and Soft-tissue infections in an Ambulatory Setting

BACKGROUND: Intravenous (IV) vancomycin is commonly used to treat MRSA (methicillin-resistant Staphylococcus aureus) infections and is typically dosed at 15 mg/kg every 12 hours. Pharmacokinetic studies, animal models, and limited human study suggest that once-daily high dose (30 mg/kg) vancomycin i...

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Detalles Bibliográficos
Autores principales: Wong, Maggie, Chapman, Michael G, Malhotra, Sangita, Mirzanejad, Yazdan, Deans, Gregory D
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631202/
http://dx.doi.org/10.1093/ofid/ofx163.805