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SCY-078 Demonstrates Significant Antifungal Activity in a Murine Model of Invasive Aspergillosis

BACKGROUND: Azoles are the most common anti-fungal agents for the treatment of Aspergillus infections. Echinocandins have demonstrated utility in Aspergillus infections, but are limited in use due to a lack of oral bioavailability. SCY-078 is a novel, oral and intravenous (IV), triterpenoid glucan s...

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Detalles Bibliográficos
Autores principales: Borroto-Esoda, Katyna, Barat, Stephen, Angulo, David, Holden, Kirsty, Warn, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631313/
http://dx.doi.org/10.1093/ofid/ofx163.1207