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SCY-078 Demonstrates Significant Antifungal Activity in a Murine Model of Invasive Aspergillosis
BACKGROUND: Azoles are the most common anti-fungal agents for the treatment of Aspergillus infections. Echinocandins have demonstrated utility in Aspergillus infections, but are limited in use due to a lack of oral bioavailability. SCY-078 is a novel, oral and intravenous (IV), triterpenoid glucan s...
Autores principales: | Borroto-Esoda, Katyna, Barat, Stephen, Angulo, David, Holden, Kirsty, Warn, Peter |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Oxford University Press
2017
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631313/ http://dx.doi.org/10.1093/ofid/ofx163.1207 |
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