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Diol-Based Polymer Microparticles for Treatment of Cutaneous Aspergillosis in an Immunocompromised Murine Model

BACKGROUND: Local delivery of antifungals may allow for high concentrations of therapeutic directly in wound beds infected with invasive fungi. In this work, microparticles (MPs) fabricated from a novel biodegradable polymer synthesized from 1,10-decanediol (DD) and fumaric acid were leveraged for t...

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Detalles Bibliográficos
Autores principales: Tatara, Alexander, Albert, Nathaniel, Watson, Emma, Mikos, Antonios, Kontoyiannis, Dimitrios P
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631439/
http://dx.doi.org/10.1093/ofid/ofx163.1226