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Phase 1 Clinical Trial of a Replication-Defective Human Cytomegalovirus (CMV) Vaccine

BACKGROUND: Congenital CMV remains an unmet medical need worldwide. Naturally acquired CMV immunity in women prior to pregnancy has been shown effective in reducing maternal-fetal transmission. V160 is engineered as a replication-defective CMV, and its replication in culture is controlled by a synth...

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Detalles Bibliográficos
Autores principales: Adler, Stuart, Lewis, Nicole, Conlon, Anthony, Christiansen, Mark, Al-Ibrahim, Mohamed S, Rupp, Richard, Fu, Tong Ming, Bautista, Oliver, Tang, Huaping, Culp, Timothy, Das, Rituparna, Beck, Karen, Tamms, Gretchen, Musey, Luwy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631465/
http://dx.doi.org/10.1093/ofid/ofx163.718