Immune Senescence Factors Associated with the Immunogenicity of a Live Attenuated Zoster Vaccine (ZV) in Older Adults

BACKGROUND: ZV confers protection against herpes zoster by increasing the cell-mediated immunity (CMI) to varicella-zoster virus (VZV). ZV immunogenicity and protection decrease with increasing age. We investigated effects of age and immune senescence on ZV immunogenicity. METHODS: 399 adults ≥50 ye...

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Detalles Bibliográficos
Autores principales: Weinberg, Adriana, Schamder, Kenneth, Johnson, Michael, Popmihajlov, Zoran, Tovar-Salazar, Adriana, Caldas, Yupanqui, Pang, Lei, Cho, Alice, Levin, Myron
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Abstracts
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631485/
http://dx.doi.org/10.1093/ofid/ofx163.1036

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631485/
http://dx.doi.org/10.1093/ofid/ofx163.1036

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