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Efficacy of Lefamulin Against Staphylococcus aureus-Induced Bacteremia in a Neutropenic and Immunocompetent Murine Model
BACKGROUND: S. aureus (SA) is a major human pathogen that causes invasive, clinical infections including bacteremia. Lefamulin (LEF) is the first semi-synthetic, pleuromutilin antibiotic for IV and oral use in humans. LEF is currently in Phase 3 trials for the treatment of community-acquired bacteri...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631522/ http://dx.doi.org/10.1093/ofid/ofx163.1205 |