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Investigating Immune Correlates of Protection to Tuberculosis Using an Ultra-Low Dose Infection in a Mouse Model
BACKGROUND: Mycobacterium tuberculosis (M.tb) is the leading infectious cause of mortality; however, there is no vaccine that confers lasting protection. To investigate the immune response to M.tb, we have developed an ultra-low dose (ULD) infection model in mice that better reflects the heterogeneo...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2017
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631853/ http://dx.doi.org/10.1093/ofid/ofx162.112 |