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Investigating Immune Correlates of Protection to Tuberculosis Using an Ultra-Low Dose Infection in a Mouse Model

BACKGROUND: Mycobacterium tuberculosis (M.tb) is the leading infectious cause of mortality; however, there is no vaccine that confers lasting protection. To investigate the immune response to M.tb, we have developed an ultra-low dose (ULD) infection model in mice that better reflects the heterogeneo...

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Detalles Bibliográficos
Autores principales:	Gern, Benjamin, Plumlee, Courtney, Gerner, Michael, Urdahl, Kevin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2017
Materias:	Abstracts
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631853/ http://dx.doi.org/10.1093/ofid/ofx162.112

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