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Immune Microenvironments of Anal Cancer Precursors Differ by HIV-Serostatus and are Associated with Ablation Outcomes

BACKGROUND: HPV-associated anal cancer precursors (high-grade squamous intraepithelial lesions, HSIL) follow a more virulent course in HIV+ patients than in their HIV− counterparts. This study aims to characterize the subpopulations of mucosa-infiltrating T lymphocytes in HSIL microenvironments, cor...

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Detalles Bibliográficos
Autores principales: Gaisa, Michael, Liu, Yuxin, Arens, Yotam, Sigel, Keith
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5631946/
http://dx.doi.org/10.1093/ofid/ofx163.425