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Pharmacokinetics of Ceftazidime/Avibactam Following Intravenous Administration in Rabbits: Developing the Preclinical Foundation for Treatment of KPC-Kp Pneumonia in Immunocompromised Patients

BACKGROUND: CRE have been identified by the CDC as one of three urgent antibiotic resistance threats. The international emergence of these pathogens has largely been driven by the dissemination of carbapenemase-producing Klebsiella pneumoniae (KPC-Kp), through enzymes that hydrolyze carbapenems and...

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Detalles Bibliográficos
Autores principales: Petraitis, Vidmantas, Petraitiene, Ruta, Satlin, Michael, Maung, Bo Bo Win, Khan, Farehin, Mazur, Chase, Georgiades, Benjamin, Hayden, Joshua A, Walsh, Thomas J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632020/
http://dx.doi.org/10.1093/ofid/ofx163.660