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Mechanisms of Flucytosine Resistance in Cryptococcus gattii May Be Independent of the FCY2-FCY1-FUR1 Pathway

BACKGROUND: Cryptococcosis is an opportunistic fungal infection caused by both Cryptococcus neoformans and its sibling species, Cryptococcus gattii. Flucytosine (5FC) is one of the most widely used antifungals against Cryptococcus spp., yet very few studies have looked at the molecular mechanisms re...

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Detalles Bibliográficos
Autores principales: Vu, Kiem, Thompson, George R, Roe, Chandler, Sykes, Jane, Dreibe, Elizabeth, Lockhart, Shawn, Meyer, Wieland, Engelthaler, David M, Gelli, Angie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632066/
http://dx.doi.org/10.1093/ofid/ofx163.134