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P2X7 Receptors Drive Spine Synapse Plasticity in the Learned Helplessness Model of Depression
BACKGROUND: Major depressive disorder is characterized by structural and functional abnormalities of cortical and limbic brain areas, including a decrease in spine synapse number in the dentate gyrus of the hippocampus. Recent studies highlighted that both genetic and pharmacological invalidation of...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Oxford University Press
2017
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632310/ https://www.ncbi.nlm.nih.gov/pubmed/28633291 http://dx.doi.org/10.1093/ijnp/pyx046 |