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Inhibitory effect of saliva on osteoclastogenesis in vitro requires toll-like receptor 4 signaling

OBJECTIVES: Saliva can suppress osteoclastogenesis, but the underlying mechanism has not been discovered yet. Considering that endotoxins suppress osteoclastogenesis in bone marrow cultures and that saliva contains endotoxins, it was reasonable to hypothesize that the impact of saliva on osteoclasto...

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Detalles Bibliográficos
Autores principales: Müller, Heinz-Dieter, Caballé-Serrano, Jordi, Lussi, Adrian, Gruber, Reinhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632348/
https://www.ncbi.nlm.nih.gov/pubmed/28101679
http://dx.doi.org/10.1007/s00784-016-2041-7