AMPK and SIRT1 activation contribute to inhibition of neuroinflammation by thymoquinone in BV2 microglia

Thymoquinone is a known inhibitor of neuroinflammation. However, the mechanism(s) involved in its action remain largely unknown. In this study, we investigated the roles of cellular reactive oxygen species (ROS), 5′ AMP-activated protein kinase (AMPK) and sirtuin 1 (SIRT1) in the anti-neuroinflammat...

Descripción completa

Detalles Bibliográficos
Autores principales: Velagapudi, Ravikanth, El-Bakoush, Abdelmeneim, Lepiarz, Izabela, Ogunrinade, Folashade, Olajide, Olumayokun A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2017
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632349/
https://www.ncbi.nlm.nih.gov/pubmed/28551846
http://dx.doi.org/10.1007/s11010-017-3064-3

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632349/
https://www.ncbi.nlm.nih.gov/pubmed/28551846
http://dx.doi.org/10.1007/s11010-017-3064-3

Ejemplares similares