Mechanisms of action and in vivo antibacterial efficacy assessment of five novel hybrid peptides derived from Indolicidin and Ranalexin against Streptococcus pneumoniae

BACKGROUND: Antimicrobial peptides (AMPs) are of great potential as novel antibiotics for the treatment of broad spectrum of pathogenic microorganisms including resistant bacteria. In this study, the mechanisms of action and the therapeutic efficacy of the hybrid peptides were examined. METHODS: TEM...

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Detalles Bibliográficos
Autores principales: Jindal, Hassan Mahmood, Zandi, Keivan, Ong, Kien Chai, Velayuthan, Rukumani Devi, Rasid, Sara Maisha, Samudi Raju, Chandramathi, Sekaran, Shamala Devi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: PeerJ Inc. 2017
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632533/
https://www.ncbi.nlm.nih.gov/pubmed/29018620
http://dx.doi.org/10.7717/peerj.3887

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5632533/
https://www.ncbi.nlm.nih.gov/pubmed/29018620
http://dx.doi.org/10.7717/peerj.3887

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